Impact of RNA modification and IL-12 boosts on mRNA-LNP vaccine-elicited CD8+ T cell responses
Sampa Santra, Michelle A. Lifton, Benjamin Mildenberg, Georgeanna Morton, Han Nhat Tran, Laura L. Sutherland, Robert Parks, Whitney Edwards, Bette Korber, Anthony T. Phan, Christopher A. Hunter, Garima Dwivedi, Benjamin Davis, Justin Su, Mohamad‐Gabriel Alameh, , Barton F. Haynes
This study compares CD8+ T cell and antibody responses in non-human primates using different ratios of modified and unmodified mRNA-LNP vaccines with IL-12 boosting.
bioRxiv · Nov 1, 2026 · PreprintImmunology