Author

Xiang Wei

Institut für Kardiovaskuläre Physiologie und Pathophysiologie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Cancer Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Almke BaderiD· 3 shared Daniela BegandtiD· 3 shared Annette Zehrer· 2 shared Barbara WalzogiD· 2 shared Bettina SchmidiD· 2 shared Jincheng GaoiD· 2 shared Mathis RichteriD· 2 shared Oliver SoehnleiniD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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3 shared papersPhysiology

Almke BaderORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

IL-1α drives a tumor-stroma-neutrophil axis through inflammatory fibroblast activation in head and neck cancer

Eva-Maria Hanschmann, Kirsten Bruderek, Francisca Hofmann-Vega, Mathias Schmidt, Bettina Budeus, Wibke Oberlies, Xiang Wei, Mathis Richter, Simon Lemm, Jagoda Agnieszka Szlachetko, Sarah Ryan, Almke Bader, Anke Daser, S Lang, Daniela Begandt, , Sven Brandau

This study identifies IL-1α as a driver of a tumor-stroma-neutrophil axis in HNSCC by inducing inflammatory fibroblast activation, enhancing neutrophil recruitment and infiltration.

bioRxiv · Jan 22, 2026 · PreprintCancer Biology

Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis

Jincheng Gao, Almke Bader, Monika I. Linder, Jingyuan Cheng, Mathis Richter, Raul Da Costa, Annette Zehrer, Karl Mitt, Bastian Popper, Felix Meissner, Xiang Wei, Enrique de Vega Gomez, Megumi Tatematsu, Meino Rohlfs, Stephanie Frenz-Wiessner, , Daniela Begandt

This study shows that VPS18 mutations disrupt neutrophil maturation by impairing vesicle dynamics and autophagy, leading to neutropenia and recurrent infections.

Cell Death and Disease · Jan 12, 2026Peer-reviewedPhysiology

SCAMP3 is essential for proper formation and function of neutrophil granules

Almke Bader, Jincheng Gao, Nina Reiter, Devon Siemes, Annette Zehrer, Xiang Wei, Ingrid Hepper, Enrique de Vega Gómez, Bettina Schmid, Ignasi Forné, Daniel Robert Engel, Barbara Walzog, Daniela Begandt

The paper shows SCAMP3 is essential for neutrophil granule formation and function, with Scamp3-deficient neutrophils showing impaired bacterial killing in vitro.

Journal of Leukocyte Biology · Oct 31, 2025Peer-reviewedPhysiology

Vitamin D regulates olfactory function via dual transcriptional and mTOR-dependent translational control of synaptic proteins

Ren Pengcheng, Cao Renhe, Xiayan Ye, Pang Wenbin, Qingshang Bi, Meihui Huang, Qionglin Zhou, Dan Ye, Xiang Wei, Le Xiao

This study shows vitamin D regulates olfactory function through both transcriptional and mTOR-dependent translational control of synaptic proteins in mice.

bioRxiv · May 2, 2025 · PreprintNeuroscience