Author

Xiangyu Liao

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Assay:spatial transcriptomics· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Jin-Chong XuiD· 2 shared Alex M. CasellaiD· 1 shared Alina Yang· 1 shared Anup MahurkariD· 1 shared Brian Caffo· 1 shared Brian R. HerbiD· 1 shared C. Korin BulleniD· 1 shared Carlo ColantuoniiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Jin-Chong XuORCID

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2 papers

Recent·Most cited

A Curated Compendium of Transcriptomic Data for the Exploration of Neocortical Development

Shreyash Sonthalia, Brian R. Herb, Ricky S. Adkins, Joshua Orvis, Jinrui Liu, Xiangyu Liao, Qingjie Yu, Xoel Mato-Blanco, Alex M. Casella, Genevieve Stein-O’Brien, Brian Caffo, Ronna P. Hertzano, Anup Mahurkar, Jin-Chong Xu, Jesse A Gillis, , Carlo Colantuoni

The paper compiles a large transcriptomic dataset of neocortical development and uses joint matrix decomposition to identify conserved transcriptome dynamics across mammals and developmental stages.

Nature Neuroscience · Mar 25, 2026Peer-reviewedNeuroscience

APOE genotype confers context dependent neurovascular vulnerability in immune-vascularized human forebrain organoids

Haohui Fang, Xiangyu Liao, C. Korin Bullen, Ruoyan Pu, Hu Wang, Juliana Condoleo, Sueanne Cheat, Xueyi Chen, Yanjun Zhang, Sonya Zhang, Da Huo, Kadia Lissit, Alina Yang, Kateri Jarvis, Stewart Neifert, , Jinchong Xu

This study shows that APOE genotype affects neurovascular vulnerability in human forebrain organoids under viral stress, with APOE2/2 and APOE4/4 showing distinct inflammatory and vascular responses.

bioRxiv · May 8, 2025 · PreprintNeuroscience