Author

Da Huo

Johns Hopkins UniversityORCID 0000-0002-6530-0632Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alina Yang· 2 shared Jin-Chong XuiD· 2 shared Sonya Zhang· 2 shared Ted M. DawsoniD· 2 shared Valina Lynn DawsoniD· 2 shared Yuejia Huang· 2 shared C. Korin BulleniD· 1 shared Haohui Fang· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersNeuroscience

Alina Yang

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintMay 8, 2025

Spatially Organized IGF1 mTOR Signaling Controls Human Forebrain Progenitor Fate Through Coordinated Transcriptional and Translational Programs

Kadia Lisst, Da Huo, Stephen M. Eacker…·Jin-Chong Xu

This study identifies a spatially organized IGF1-mTOR signaling mechanism in human forebrain progenitors that regulates proliferation and fate through transcriptional and translational control.

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 8, 2025

APOE genotype confers context dependent neurovascular vulnerability in immune-vascularized human forebrain organoids

Haohui Fang, Xiangyu Liao, C. Korin Bullen…·Jinchong Xu

This study shows that APOE genotype affects neurovascular vulnerability in human forebrain organoids under viral stress, with APOE2/2 and APOE4/4 showing distinct inflammatory and vascular responses.

2 citations

humanspatial transcriptomics

𝕏 PostBluesky