Author

Yanjun Zhang

Johns Hopkins University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Biochemistry· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:spatial transcriptomics· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Alina Yang· 1 shared Andrew PettiiD· 1 shared Bin LiuiD· 1 shared C. Korin BulleniD· 1 shared Da HuoiD· 1 shared Erik J. SontheimeriD· 1 shared Haohui Fang· 1 shared Haoyang ChengiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperNeuroscience

Alina Yang

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2 papers

Recent·Most cited

Prime assembly with linear DNA donors enables large genomic insertions

Bin Liu, Andrew Petti, Xuntao Zhou, Haoyang Cheng, Jenny Gao, Matthew Yee, Youwei Qiao, Yanjun Zhang, Lin Mei Zhou, Scot A. Wolfe, Tingting Jiang, Erik J. Sontheimer, Wen Xue

This paper introduces a Prime Assembly method for inserting large DNA fragments into the genome, achieving efficient and precise insertions up to 11 kilobase pairs.

Nature · Apr 29, 2026Peer-reviewedBiochemistry

APOE genotype confers context dependent neurovascular vulnerability in immune-vascularized human forebrain organoids

Haohui Fang, Xiangyu Liao, C. Korin Bullen, Ruoyan Pu, Hu Wang, Juliana Condoleo, Sueanne Cheat, Xueyi Chen, Yanjun Zhang, Sonya Zhang, Da Huo, Kadia Lissit, Alina Yang, Kateri Jarvis, Stewart Neifert, , Jinchong Xu

This study shows that APOE genotype affects neurovascular vulnerability in human forebrain organoids under viral stress, with APOE2/2 and APOE4/4 showing distinct inflammatory and vascular responses.

bioRxiv · May 8, 2025 · PreprintNeuroscience