PathologybioRxivPreprint
A spatial-temporal atlas of human islet pathophysiology identifies a size-dependent trajectory from compensation to decompensation
Tengli Liu, Rui Liang, Lanqiu Zhang…·Shusen Wang
This study identifies a size-dependent trajectory of islet remodeling in T2D, showing medium and large islets correlate with glycemic failure while small islets show compensatory responses.