Author

Xingyi Yang

Emory University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 2 Microbiology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Angela Sangjizhuoma· 2 shared Anthony K. L. LeungiD· 2 shared Jing HeiD· 2 shared Mohsen BadieeiD· 2 shared Adriana GalvaniD· 1 shared Andrew MehleiD· 1 shared Charina S. FabilaneiD· 1 shared Che-Yuan Chang· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersNeuroscience

Angela Sangjizhuoma

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Caudate nucleus aging and its association with brain disorders

Shuai Guo, Xingyi Yang, Yi Dong, Jixiang Xu, Angela Sangjizhuoma, Thomas Wichmann, Adriana Galvan, Yoland Smith, Jing He

This study examines caudate nucleus aging across species and diseases, identifying shared and disorder-specific age-related changes in cell types and regulatory features.

bioRxiv · Nov 3, 2026 · PreprintNeuroscience

Integrative drug discovery for Parkinson disease with DIMER

Shuai Guo, Xingyi Yang, Yi Dong, Lidong Yu, Angela Sangjizhuoma, Ka Lok Sie, Keyun Zhu, Yiying Zhang, Xiyuan Zhao, Ella Kerman, Ruonan Li, Jing He

The paper introduces DIMER, a framework for drug repurposing and virtual screening in Parkinson's disease, identifying 423 candidates and validating four in organoids.

bioRxiv · Oct 29, 2026 · PreprintNeuroscience

Global remodeling of ADP-ribosylation by PARP1 suppresses influenza A virus infection

Zhenyu Zhang, Isabel R. Uribe, Kaitlin A. Davis, Robert Lyle McPherson, Gloria P. Larson, Mohsen Badiee, Vy Tran, Mitchell P. Ledwith, Elizabeth M Feltman, Shuǐqìng Yú, Yíngyún Caì, Che-Yuan Chang, Xingyi Yang, Zhuo Ma, Paul Chang, , Andrew Mehle

The paper shows influenza A virus infection increases global ADP-ribosylation, which inhibits viral replication, and identifies PARP1 as the main enzyme involved, with NS1 counteracting this effect.

Nature Communications · Dec 17, 2025Peer-reviewedMicrobiology

Transient Poly(ADP-Ribose) Triggers FUS Condensation Hysteresis via a Prion-Like Mechanism

Hongrui Liu, Yuxuan Cai, Leilei Shi, Meenakshi Pillai, Nilimesh Das, Haley E. Tarbox, Yingda Ge, Kun Yue, Xingyi Yang, Piyush Rath, Mohsen Badiee, Charina S. Fabilane, Jamie B. Spangler, Mark T. Bedford, Sua Myong, , Anthony K. L. Leung

The paper shows PAR induces a conformational switch in FUS, enabling sustained condensation through N-terminal PrLD interactions after PAR degradation.

bioRxiv · Jul 3, 2025 · PreprintMolecular Biology