Author
Johns Hopkins UniversityORCID 0000-0003-3722-4609Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Zhenyu Zhang, Isabel R. Uribe, Kaitlin A. Davis…·Andrew Mehle
The paper shows influenza A virus infection increases global ADP-ribosylation, which inhibits viral replication, and identifies PARP1 as the main enzyme involved, with NS1 counteracting this effect.
Hongrui Liu, Yuxuan Cai, Leilei Shi…·Anthony K. L. Leung
The paper shows PAR induces a conformational switch in FUS, enabling sustained condensation through N-terminal PrLD interactions after PAR degradation.
Tamara Maiuri, Carlos Barba Bazan, Rachel Harding…·Ray Truant
The paper identifies a deficient PAR response in Huntington disease patients, suggesting a potential therapeutic target for early intervention.
Tong Wang, Kush Coshic, Mohsen Badiee…·Anthony K. L. Leung
This study investigates how the length of poly(ADP-ribose) (PAR) affects its structural transitions in the presence of Mg2+ ions, revealing length-dependent compaction and bundle formation.