Endocardial TIE1 synergizes with TIE2 to regulate the atrial internal muscular network assembly
Kai Ding, Beibei Xu, Xinhao Yu, Xiwen Jia, Taotao Li, Xin Shen, Junda Li, Xudong Cao, Yahui Liu, Zhen Zhang, Yulong He
This study shows TIE1 and TIE2 work together in atrial development, with TIE1 specifically needed for atrial muscular network formation.
bioRxiv · Sep 3, 2026 · PreprintDevelopmental Biology