Neurosciencenpj Parkinson s DiseasePeer-reviewed
Protein aggregation inhibitors induce divergent transcriptional responses in a cellular model of a-synuclein seeded aggregation
Paulien Van Minsel, Chris Van den Haute, Eline Vonck…·Wouter Peelaerts
The paper evaluates three Syn aggregation inhibitors in a cellular model of a-synuclein aggregation using single-cell RNA sequencing to identify transcriptional changes and potential druggable pathways.