Author

Y. Dhingra

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

D. G. Sashital· 2 shared P. Juneja· 1 shared S. K. Suresh· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBiochemistry

D. G. Sashital

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2 papers

Recent·Most cited

Cas4/1 dual nuclease activities enable prespacer maturation and directional integration in a type I-G CRISPR-Cas system

Y. Dhingra, D. G. Sashital

This study identifies a type I-G CRISPR-Cas system where Cas4/1 fusion protein performs dual nuclease activities for prespacer maturation and directional integration.

bioRxiv · Jun 5, 2023Biochemistry

PAM binding ensures orientational integration during Cas4-Cas1-Cas2 mediated CRISPR adaptation

Y. Dhingra, S. K. Suresh, P. Juneja, D. G. Sashital

This study determines the cryo-EM structures of the Cas4-Cas1-Cas2 complex, revealing how PAM binding ensures correct spacer orientation during CRISPR adaptation.

bioRxiv · May 30, 2022Biochemistry