The biosynthetic-secretory pathway, supplemented by recycling routes, specifies epithelial membrane polarity
N. Zhang, H. Zhang, L. A. Khan, G. Jafari, Y. Eun, E. Membreno, V. Gobel
The paper identifies trafficking molecules that polarize apical membranes and PAR complexes, showing biosynthetic-secretory pathways asymmetrically expand the apical domain before PARs.
bioRxiv · Jan 6, 2022 · PreprintCell Biology