BiophysicsbioRxiv
Specific decreasing of Na+ channel expression on the lateral membrane of cardiomyocytes causes fatal arrhythmias in Brugada syndrome
K. Tsumoto, T. Ashihara, N. Naito…·Y. Kurachi
This study shows that reduced Na+ channel expression in the lateral membrane of cardiomyocytes leads to phase-2 reentry, causing lethal arrhythmias in Brugada syndrome.
DOI 10.1038/s41598-020-76681-3