Author

Y. M. Wang

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Srikanth SingamaneniiD· 2 shared Anthony J. BleyeriD· 1 shared Avishek DebnathiD· 1 shared Chenjian Gu· 1 shared Chuang Li· 1 shared Clay F. SemenkovichiD· 1 shared Eric TyckseniD· 1 shared Fumihiko UranoiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersGenetics

Srikanth SingamaneniORCID

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2 papers

Recent·Most cited

MANF Clears Mutant Uromodulin in Human Kidney Organoids of Autosomal Dominant Tubulointerstitial Kidney Disease

Chenjian Gu, Yili Fang, Y. M. Wang, Eric Tycksen, Gayathri Kondepati, Chuang Li, Kendrah O. Kidd, Jun Liu, Fumihiko Urano, Maria Lindahl, Anthony J. Bleyer, Srikanth Singamaneni, Zhao Qing Sun, Ying Maggie Chen

This study shows MANF reduces mutant uromodulin in kidney organoids by enhancing autophagy through IP3R1 repression, suggesting potential for treating ADTKD and similar protein misfolding diseases.

Journal of Clinical Investigation · Aug 25, 2026Peer-reviewedGenetics

Palmitoylation calibrates mitochondrial transport of insulin across the endothelium in insulin resistance

Wei Zhang, Sangeeta Adak, Qiang Zhang, Gulinu Maimaituxun, Rong Xu, Guifang Dong, Avishek Debnath, Y. M. Wang, Srikanth Singamaneni, Xiaochao Wei, Clay F. Semenkovich

This study shows that palmitoylation regulates mitochondrial transport of insulin across the endothelium, improving insulin sensitivity in insulin resistance.

bioRxiv · Jul 20, 2026 · PreprintPhysiology