Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut
E. Bakkeren, J. A. Herter, J. S. Huisman, Y. Steiger, E. Gul, J. P. M. Newson, A. O. Brachmann, J. Piel, R. R. Regoes, S. Bonhoeffer, M. Diard, W.-D. Hardt
This study shows that plasmid dissemination in the gut is enhanced by antibiotic degradation in the lumen and cycling between gut and tissue reservoirs in Salmonella Typhimurium.
bioRxiv · Apr 8, 2021Evolutionary Biology