Author

Y.-J. Chang

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

L. Chen· 2 shared A. E. Obr· 1 shared A. Lemenze· 1 shared C.-H. Wang· 1 shared C.-W. Hu· 1 shared D. LeRoith· 1 shared E. Gallagher· 1 shared H. G. Rylander· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCancer Biology

L. Chen

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Nucleic Acid Adductomics - the Next Generation of Adductomics for Assessing Environmental Health Risk

M. S. Cooke, Y.-J. Chang, Y.-R. Chen, C.-W. Hu, M.-R. Chao

This paper introduces a comprehensive NA adductomics approach to assess environmental exposures by analyzing DNA and RNA modifications in urine, revealing over 1,000 modified nucleic acid moieties.

bioRxiv · Mar 24, 2022 · PreprintPharmacology & Toxicology

Breast tumor IGF-1R regulates cell adhesion and metastasis: Alignment of mouse single cell and human breast cancer transcriptomics

A. E. Obr, Y.-J. Chang, V. Ciliento, A. Lemenze, K. Maingrette, J. J. Bulatowicz, Q. Shang, E. Gallagher, D. LeRoith, T. L. Wood

The paper investigates how reduced IGF-1R expression affects metastasis in breast cancer by analyzing human and mouse transcriptomic data.

bioRxiv · Aug 31, 2021 · PreprintCancer Biology

Deep learning enables rapid and robust analysis of fluorescence lifetime imaging in photon-starved conditions

Y.-I. Chen, Y.-J. Chang, S.-C. Liao, T. D. Nguyen, J. Yang, Y.-A. Kuo, S. Hong, Y.-L. Liu, H. G. Rylander, S. R. Santacruz, T. E. Yankeelov, H.-C. Yeh

This paper introduces flimGANE, a deep learning method that rapidly and accurately generates FLIM images in low-photon conditions, outperforming traditional methods in speed and analysis accuracy.

bioRxiv · Dec 2, 2020 · PreprintCell Biology

Mitochondrial ROS1 increases mitochondrial fission and respiration in oral squamous cancer carcinoma

Y.-J. Chang, K.-W. Chen, L. Chen

This study shows that ROS1 in oral squamous cell carcinoma localizes to mitochondria, enhancing fission and respiration, which promotes cancer invasiveness.

Cancers · Oct 1, 2020Peer-reviewedCancer Biology

Discovery of isoplumbagin as a novel NQO1 substrate and anti-cancer quinone

Y.-C. Tsao, Y.-J. Chang, C.-H. Wang, L. Chen

This study identifies isoplumbagin as a novel NQO1 substrate that exerts anti-cancer effects by modulating mitochondrial function and dynamics in multiple cancer cell lines.

bioRxiv · Apr 28, 2020Pharmacology & Toxicology