Cell BiologybioRxiv
The targeted cytosolic degradation of class I histone deacetylases is essential for efficient alphaherpesvirus replication
Sheng‐Li Ming, Meng-Hua Du, Jia-Ming Yang…·Bei‐Bei Chu
This study shows alphaherpesviruses degrade class I HDACs to activate DDR and enhance replication, identifying potential therapeutic targets.
DOI 10.7554/elife.110309