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Yacine Seffal

PROTEO

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Evolutionary Biology· 1

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Approach:experimental assay· 1

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Alexandre K. DubéiD· 1 shared Angel F. CisnerosiD· 1 shared Christian R. LandryiD· 1 shared Florian Mattenburger· 1 shared Isabelle Gagnon‐ArsenaultiD· 1 shared Lou Nielly‐ThibaultiD· 1 shared María Camila Muñoz Vega· 1 shared Maria del Mar Varela Vasquez· 1 shared

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Alexandre K. DubéORCID

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Evolutionary BiologybioRxivPreprintJun 13, 2025

Paralog interference contributes to the preservation of genetic redundancy

Angel F. Cisneros, Florian Mattenburger, Isabelle Gagnon‐Arsenault…·Christian R. Landry

The paper shows that paralog interference enhances negative selection on loss-of-function mutations, preserving genetic redundancy over longer timescales.

2 citations

experimental assay

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