Systems BiologybioRxivPreprint
TNF signalling fine-tunes Langerhans cell transcriptional programmes mediating adaptive immunity.
James Davies, Andrés F. Vallejo, Sofía Sirvent…·Marta Ewa Polak
The paper identifies TNF-driven transcriptional programs in Langerhans cells that regulate immunogenic and tolerogenic responses through IRF1 and other transcription factors.