Yan Jin

Identification of srh-30 as a 2-nonanone receptor in C. elegans

The paper identifies srh-30 as a receptor for 2-nonanone in C. elegans using single-cell expression data and genetic validation.

STIMscope: centimeter-scale all-optical imaging and patterned optogenetic manipulation at single-cell resolution

The paper introduces STIMscope, a low-cost, open-source platform for all-optical imaging and optogenetic manipulation at single-cell resolution, validated in multiple biological systems.

A Locus Control Region Generates Distinct Active Placental Lactogen And Inactive Growth Hormone Gene Domains In Term Placenta That Are Disrupted With Obesity

The paper shows that PEG3 binding to the hPL locus control region influences hPL gene expression in placenta, with changes in maternal obesity and diabetes affecting this interaction.

Increased capacity to maintain glucose homeostasis in a transgenic mouse expressing human but not mouse growth hormone with developing high fat diet-related insulin resistance, steatosis and adipose dysfunction

This study compares the effects of human and mouse growth hormone on glucose homeostasis in transgenic mice fed high fat diets, finding initial resistance to insulin resistance in human GH-expressing mice.

A conserved N-terminal motif of CUL3 mediates assembly and licenses E3 ligase activation of CRL3KLHL22

The paper identifies a conserved N-terminal motif in CUL3 that mediates dimerization and activates CRL3KLHL22 E3 ligase function.