Author

Yan Yu

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Neuroscience· 2 Bioinformatics· 1 Biophysics· 1 Genetic & Genomic Medicine· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:imaging· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Alisa F. ZyryanovaiD· 1 shared Amada Abrego· 1 shared Anders GunnarssoniD· 1 shared Anthony D. KeefeiD· 1 shared Bo Wei· 1 shared Briana Popeney· 1 shared Chao ZhangiD· 1 shared Christopher D. HuppiD· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperMolecular Biology

Alisa F. ZyryanovaORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

BioIMA: a one-click desktop tool for standardized extraction of phenotypic traits from biological images

Xiner Qumu, Xuming Dan, Jianju Feng, Yangkai Cui, Yi Gong, Yukang Hou, Qiang Lai, Zeng Wang, Yulin Zhang, Yiman Zhu, Yan Yu, Feng Zhang, Marco Todesco, Jing Wang

BioIMA is a desktop tool that automates phenotypic trait extraction from biological images, achieving high accuracy and speed compared to manual methods.

bioRxiv · Sep 3, 2026 · PreprintBioinformatics

A molecular stabiliser of an inhibitory eIF2B-eIF2(αP) complex activates the Integrated Stress Response

Fiona Shilliday, Miguel Gancedo-Rodrigo, Ginto George, Shintaro Aibara, Santosh Adhikari, Syedah Neha Ashraf, Evelyne J. Barrey, Damian C. Crowther, Paige Dickson, Diana Gikunju, Marie-Aude Guié, John P. Guilinger, Anders Gunnarsson, Heather P. Harding, Christopher D. Hupp, , John E. Linley

The paper identifies a chemical inhibitor of eIF2B that activates the Integrated Stress Response by stabilizing an inhibitory complex with phosphorylated eIF2.

Nature Communications · May 6, 2026Peer-reviewedMolecular Biology

Nanocluster-Mediated Signaling Crosstalk between FcγR and TLR4 in Macrophage Inflammatory Responses

Seonik Lee, Hunter Richman, Yan Yu

This study investigates how TLR4 and FcγR interact on macrophage surfaces through nanoclusters to enhance inflammatory responses and signaling.

Scientific Reports · Apr 14, 2025Peer-reviewedBiophysics

Genome-wide association and Mendelian randomisation analysis among 30,699 Chinese pregnant women identifies novel genetic and molecular risk factors for gestational diabetes and glycaemic traits

Jianxin Zhen, Yuqin Gu, Piao Wang, Weihong Wang, Shengzhe Bian, Shujia Huang, Hui Liang, Mingxi Huang, Yan Yu, Qing Chen, Guozhi Jiang, Xiu Qiu, Likuan Xiong, SiYang Maggie Liu

This study identifies four genetic loci associated with gestational diabetes risk and 31 loci linked to glycaemic traits in 30,699 Chinese pregnant women, with MTNR1B showing the strongest association.

Diabetologia · Feb 19, 2024Peer-reviewedGenetic & Genomic Medicine

Multiplexed code of navigation variables in the anterior limbic system

Jean Laurens, Amada Abrego, Henry Cham, Briana Popeney, Yan Yu, Naama Rotem, Janna Aarse, Eftihia K. Asprodini, J. David Dickman, Dora E. Angelaki

The paper uses a multimodal model to analyze how neurons in specific brain regions of mice encode navigational variables during foraging, revealing new coding patterns in the anterior thalamus and retrosplenial cortex.

bioRxiv · Oct 5, 2019 · PreprintNeuroscience

Gut Microbiota in male patients with chronic traumatic complete spinal cord injury

Chao Zhang, Wenhao Zhang, Jie Zhang, Yingli Jing, Mingliang Yang, Liangjie Du, Feng Gao, Huiming Gong, Liang Chen, Jun Li, Hongwei Liu, Chuan Qin, Yanmei Jia, Jiali Qiao, Bo Wei, , Jianjun Li

This study analyzes gut microbiota differences between healthy adults and chronic traumatic complete SCI patients, finding dysbiosis linked to serum biomarkers and neurogenic bowel dysfunction.

Journal of Translational Medicine · Dec 1, 2018Peer-reviewedNeuroscience