Yang Sun

A GPX4 phosphorylation switch by FGFR1 guards against ferroptosis

This study identifies a phosphorylation switch controlled by FGFR1 that regulates GPX4 activity and protects against ferroptosis in cardiac ischemia/reperfusion injury.

A 3D in vitro follicle-endometrial organoid co-culture model recapitulates ovarian control of human endometrial decidualization

This paper develops a 3D in vitro model of ovarian follicle-endometrial organoid co-culture that mimics ovarian control of endometrial decidualization, showing similar but distinct transcriptional patterns compared to traditional hormone-based methods.

Genetic loss of JAK1 and cutaneous HPV infection

The paper identifies JAK1 loss-of-function variants in patients with epidermodysplasia verruciformis, linking them to susceptibility to cutaneous HPV infection and impaired antiviral immunity.

The Effects of Different Gait Patterns on Knee Joint Biomechanics and Dynamic Stability during Stair Walking in Healthy Adults

This study compares knee joint biomechanics and dynamic stability during stair ascent using single-step and cross-step gait patterns in healthy adults, finding that cross-step reduces stability and increases joint stress.

p.D372H: A novel SCN5A mutation associated with Brugada syndrome

The paper identifies a novel SCN5A mutation, D372H, associated with Brugada syndrome and demonstrates its functional impact on sodium channel activity and expression.