Author

Yi Ding

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

Daniel A. SchmitziD· 2 shared Jun WuiD· 2 shared Leqian YuiD· 2 shared Masahiro SakuraiiD· 2 shared Yulei WeiiD· 2 shared Ashwani KumariD· 1 shared Aziza K. Chedrawi· 1 shared Baiquan CiiD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersDevelopmental Biology

Daniel A. SchmitzORCID

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3 papers

Recent·Most cited

Metabolic dysfunction related to specific genetic variant sites of methylmalonic acidemia

Haijuan Zhi, Yuxin Deng, Yi Ding, Ting Chen, Bohui Zhou, Yue Cao, Siyu Chang, Xia Zhan, Feng Xu, Lili Hao, Lili Liang, Wenjuan Qiu, Huiwen Zhang, Xuefan Gu, Lianshu Han

The paper investigates metabolic differences in methylmalonic acidemia subtypes caused by specific genetic variants, identifying enriched metabolites associated with each mutation.

bioRxiv · Dec 17, 2025 · PreprintMolecular Biology

An inappropriate decline in ribosome levels drives a diverse set of neurodevelopmental disorders

Chunyang Ni, Leqian Yu, Barbara Vona, Dayea Park, Yulei Wei, Daniel A. Schmitz, Yudong Wei, Yi Ding, Masahiro Sakurai, Emily B. Ballard, Yan Liu, Ashwani Kumar, Chao Xing, Hyung‐Goo Kim, Cumhur Gökhan Ekmekçi, , Michael Buszczak

The paper identifies how reduced ribosome levels in neural progenitor cells contribute to neurodevelopmental disorders and shows that mTOR activation can alleviate these defects.

bioRxiv · Jan 9, 2024 · PreprintDevelopmental Biology

Dissecting embryonic and extra-embryonic lineage crosstalk with stem cell co-culture

Yulei Wei, Enbo Zhang, Leqian Yu, Baiquan Ci, Masahiro Sakurai, Lei Ming Guo, Xin Zhang, Sirui Lin, Shino Takii, Lizhong Liu, Jian Liu, Daniel A. Schmitz, Ting Su, Junmei Zhang, Qiaoyan Shen, , Jun Wu

This study establishes co-cultures of embryonic and extraembryonic stem cells to study lineage crosstalk during early mammalian development, revealing growth inhibition of pluripotent cells by extraembryonic endoderm cells.

Cell · Dec 1, 2023Peer-reviewedDevelopmental Biology