Ying Yu

Defense-associated reverse transcriptases synthesize DNA in a telomerase-like manner

This study characterizes the reverse transcription activity of DRT10 and reveals its unique 2:1 RT:ncRNA assembly and mechanism of cDNA synthesis.

Spontaneous eye behavior is an objective marker of parkinsonian severity

The paper shows that spontaneous eye behavior in a nonhuman primate PD model correlates with disease severity and beta oscillatory activity, suggesting it as a potential biomarker.

Inflammatory proteolysis generates pathogenic APOL1 fragments with distinct intracellular toxicities in podocytes derived from children with HIV associated nephropathy

The paper identifies inflammatory proteolysis of APOL1 in podocytes from HIVAN patients, generating toxic fragments with distinct pathogenic functions.

Perceiving Material Qualities from Moving Contours

This study investigates how contour motion in dynamic line drawings conveys mechanical material properties, showing that line drawings convey similar material information as fully textured stimuli.

Histone H2BK120 ubiquitination modulates PRC1 activity and H2AK119ub deposition on nucleosomes

The paper reveals how H2BK120ub enhances PRC1 activity and modulates H2AK119ub deposition, linking active and repressive histone modifications in gene regulation.

Sleep firing rate homeostasis is disrupted in mild parkinsonism

The paper investigates sleep firing rate homeostasis in a nonhuman primate model of Parkinson's disease and finds it is disrupted in parkinsonism.

Role of non-coding RNA hsa_circ_0001495 in 16HBE cellular inflammation induced by PM2.5 and O3 combined exposure

This study investigates the role of hsa_circ_0001495 in 16HBE cell inflammation caused by combined PM2.5 and O3 exposure, finding it inhibits the inflammatory response.