Why is Cyclin A degraded before Cyclin B?
Annalisa Roberti, Sofia Garcia Soto, Ynon Weiss, Theodoros I. Roumeliotis, Jyoti Sharma Choudhary, Jonathon Pines
This study shows that rapid degradation of CyclinA ensures proper chromosome congression and genomic stability by preventing aneuploidy and malformed nuclei.
bioRxiv · Oct 27, 2026 · PreprintCell Biology