Yue Xu

This study links cochlear immunity to adjacent bone marrow through anatomical and day-night profiling in mice, revealing synchronized clocks and immune cell dynamics.

The paper demonstrates that a fixed neural wiring diagram in Drosophila can store and retrieve memories through neuronal adaptation, dependent on specific brain states.

This study establishes and validates an awake longitudinal fUS-ULM-fULM framework in mice over five months, showing no significant longitudinal drift and no memory impairment or chronic neuroinflammation.

This study shows that NSD2 deficiency disrupts chromatin accessibility and gene expression in cochlear hair cells, leading to increased ECM expression and hearing impairment, which can be mitigated by ECM intervention.

The paper identifies oxidative protein states as drivers of metastatic fitness in lung cancer by linking ROS-regulated protein modifications to mitochondrial function and metastasis.

This study shows NSD2 promotes cell durotaxis and drives the transition from PKD to TCRCC via integrin/FAK/AKT signaling, with implications for targeted therapies.

This study shows that H3K36me3, catalyzed by SETD2, maintains ISC stemness by regulating lipid metabolism and preventing senescence through chromatin remodeling and metabolic intervention.

The paper shows NSD2 maintains taurine biosynthesis via FMOs in intestinal epithelial cells, preventing barrier disruption in IBD.

This study shows that SETD2 deficiency promotes renal fibrosis by activating the TGF-β/Smad signaling pathway in VHL-deficient mice.