BiochemistrybioRxivPreprint
Integrated Proteo-Metabolomics of Urinary Extracellular Vesicles Reveals Early Molecular Divergence and Temporal Pathogenesis of Sepsis-Associated AKI
Tanyu Chang, I‐Lin Tsai, Guan‐Yuan Chen…·C C K Chih-Chin Kao
This study uses longitudinal proteo-metabolomics of urinary extracellular vesicles to identify stage-specific molecular changes in sepsis-associated AKI, revealing early inflammatory and hypoxic responses followed by metabolic reprogramming.
DOI 10.64898/2026.07.23.740423