Author

Yume Mimura

Hokkaido University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Keita MatsunoiD· 3 shared Jingshu LiiD· 2 shared Jumpei ItoiD· 2 shared Kazuo TakayamaiD· 2 shared Kei SatoiD· 2 shared Keita MizumaiD· 2 shared Kumiko YoshimatsuiD· 2 shared Masumi TsudaiD· 2 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersMicrobiology

Keita MatsunoORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Reverse genetics system for emerging tick-borne orthonairovirus highlights dispensable N-terminal region of Gn associated with replication in tick vectors

Yume Mimura, Takahiro Hiono, Hiromu Arakawa, Shiori Go, Asako Shigeno, Mebuki Ito, Eri FUJII, Keita Mizuma, Ryo Nakao, Yasuko Orba, Hiroyuki Kaji, Keita Matsuno

This study develops a reverse genetics system for Yezo virus to investigate the role of its glycoprotein N-terminal region in replication across mammalian and tick hosts.

bioRxiv · Sep 29, 2026 · PreprintMicrobiology

A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity

Shuhei Tsujino, Masumi Tsuda, Sayaka Deguchi, Jumpei Ito, Taha Y. Taha, Hesham Nasser, Lei Wang, Julia Rosecrans, Rigel Suzuki, Saori Suzuki, Kumiko Yoshimatsu, Mélanie Ott, Terumasa Ikeda, Kei Sato, Kazuo Takayama, , Miki Kawano

This study identifies the non-spike R204P mutation in the SARS-CoV-2 Omicron XEC variant as a driver of increased inflammation and pathogenicity through NF-κB activation.

Nature Communications · Dec 14, 2025Peer-reviewedMicrobiology

Evolution of BA.2.86 to JN.1 reveals functional changes in non-structural viral proteins are required for fitness of SARS-CoV-2

Shuhei Tsujino, Masumi Tsuda, Naganori Nao, Kaho Okumura, Lei Wang, Yoshitaka Oda, Yume Mimura, Jingshu Li, Rina Hashimoto, Yasufumi Matsumura, Rigel Suzuki, Saori Suzuki, Kumiko Yoshimatsu, Miki Nagao, Jumpei Ito, , Takasuke Fukuhara

This study investigates the evolutionary changes from BA.2.86 to JN.1, showing that non-spike protein mutations compensate for reduced spike protein replication, enhancing viral fitness.

bioRxiv · Feb 17, 2025 · PreprintMicrobiology