Keita Matsuno

This study shows favipiravir suppresses OROV replication and disease in hamsters, preventing neuroinvasion and pathogenic host responses through transcriptomic analysis.

This study develops a reverse genetics system for Yezo virus to investigate the role of its glycoprotein N-terminal region in replication across mammalian and tick hosts.

This study maps the spatial distribution of ticks and tick-borne pathogens in central Hokkaido, Japan, and identifies ecological factors influencing their distribution.

This study identifies the non-spike R204P mutation in the SARS-CoV-2 Omicron XEC variant as a driver of increased inflammation and pathogenicity through NF-κB activation.

This paper introduces CoVFit, a protein language model that predicts SARS-CoV-2 variant fitness using spike protein sequences, identifying fitness-enhancing mutations and predicting emerging variants.

This paper establishes a reverse genetics system for feline coronavirus to generate recombinant viruses for studying pathogenesis and antiviral responses.

This study investigates the evolutionary changes from BA.2.86 to JN.1, showing that non-spike protein mutations compensate for reduced spike protein replication, enhancing viral fitness.

This study investigates the virological characteristics of the SARS-CoV-2 BA.2.86 variant, finding it has higher reproduction number than EG.5.1 but lower pathogenicity and replication capacity compared to BA.2.

This study investigates the virological properties of the SARS-CoV-2 HK.3 variant, a FLip variant with substitutions S:L455F and S:F456L, to assess its growth advantage.

The paper investigates the virological features of the SARS-CoV-2 EG.5.1 variant, finding its fitness and antiviral sensitivity comparable to XBB.1.5, with structural differences in spike proteins.

The paper investigates how avian H7 influenza A viruses can bind NeuGc through specific mutations, revealing insights into viral adaptation to NeuGc receptors.