Yunxia Guo

Ultra-fast and scalable high-resolution full-length single-cell RNA sequencing using CHART-seq

CHART-seq enables ultra-fast, scalable full-length single-cell RNA sequencing with improved gene detection and isoform annotation compared to existing methods.

snCED-seq: High-fidelity cryogenic enzymatic dissociation of nuclei for single-nucleus RNA-seq of FFPE tissues

The paper introduces snCED-seq, a method for isolating high-quality nuclei from FFPE tissues, showing improved RNA retention and gene detection compared to traditional methods.

Single-nucleus RNA sequencing revealed the impact of post-mortem interval on the cellular component and gene expression analysis of mouse brains

This study uses snRNA-seq to analyze how post-mortem interval affects cellular components and gene expression in mouse brain tissues.

Transcriptomic profiling of nuclei from PFA-fixed and FFPE brain tissues

This study evaluates how fixation and storage times affect nuclear transcriptomic profiles in FFPE brain tissues, finding that fixation time has a greater impact than storage time.

Defining specific cell states of MPTP-induced Parkinson's disease by single-nucleus RNA sequencing

This study uses single-nucleus RNA sequencing to identify PD-specific cell states in MPTP-induced mouse brains, revealing changes in astrocytes, endothelial cells, and medium spiny neurons.

Use of short-term high energy dietary for estimating transcriptional profiling of liver tissues in sheep

This study examines the effects of short-term high energy diet on liver transcriptome in sheep, identifying 622 differentially expressed genes and their involvement in metabolic pathways.