Author

Xiaofei Gao

The University of Texas Southwestern Medical CenterPrimary ORCID profile (0000-0003-2799-7421 · 2 papers)Unclaimed ORCID profile · follow to get notified of new preprints

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Xiaofei GaoiD2 papers · Westlake University

Biology Disciplines

Click to filter author papers

Neuroscience· 4 Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:mouse· 5 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:imaging· 2 Assay:metabolomics· 2

Frequent Co-Authors

Jun-Liszt LiiD· 3 shared Woo‐Ping GeiD· 3 shared Fei Chen· 2 shared Long‐Jun WuiD· 2 shared Ralph J. DeBerardinisiD· 2 shared Robert M. BachooiD· 2 shared Wenzhi SuniD· 2 shared Xiao-Ling HuiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Jun-Liszt LiORCID

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Ultra-fast and scalable high-resolution full-length single-cell RNA sequencing using CHART-seq

Wenyi Zhang, Aiqun Chen, Kaiqiang Ye, Handong Wang, Jiahao Shen, Zhe Jiao, Yunxia Guo, Yiming Xu, Dongmei Zhang, Yan Huang, Liyong He, Xiaofei Gao, Xiangwei Zhao

CHART-seq enables ultra-fast, scalable full-length single-cell RNA sequencing with improved gene detection and isoform annotation compared to existing methods.

bioRxiv · Sep 24, 2026 · PreprintGenomics

Carbohydrate adaptation drives liver-brain axis maturation

Hongmei Cui, Zheng Wu, Yuannyu Zhang, Hieu Vu, Hongli Chen, Xiaofei Gao, Yan J. Jin, Donghong Cai, Sarada Achyutuni, Phong Nguyen, Chunxiao Pan, Hui Cao, Camenzind G. Robinson, Jeffery D Steinberg, Laura J. Janke, , Min Ni

The paper shows that LACTB2 in the liver regulates mitochondrial maturation to coordinate carbohydrate metabolism with brain development in mice.

bioRxiv · Nov 5, 2025 · PreprintDevelopmental Biology

pan-ECM: live brain extracellular matrix imaging with protein-reactive dye

Xiaoqian Ge, Xueqi Xu, Qi Cai, Hejian Xiong, Chen Xie, Yi Hong, Xiaofei Gao, Yao Yao, Robert M. Bachoo, Zhenpeng Qin

The paper develops a method to image the entire brain extracellular matrix in live tissue using a protein-reactive dye, enabling visualization of ECM structures in various brain conditions.

bioRxiv · Mar 29, 2023 · PreprintNeuroscience

ADAM10 mediates macroglial cell fate decisions in the developing brain

Yihui Wang, Yue Liang, Daosheng Ai, Jun-Liszt Li, Ziyan Feng, Zhibao Guo, Xing-jun Chen, Tingting Zhang, Xiaoxiao Zou, Junli Gao, Xiaofei Gao, Xiao-Ling Hu, Long‐Jun Wu, Wenzhi Sun, Suiqiang Zhu, , Woo‐Ping Ge

The paper shows ADAM10 regulates macroglial cell fate by promoting astrocyte generation and inhibiting oligodendrocyte production in developing brains.

bioRxiv · Feb 11, 2023 · PreprintNeuroscience

Precision mapping of the mouse brain metabolome

Huanhuan Pang, Jun-Liszt Li, Xiao-Ling Hu, Fei Chen, Xiaofei Gao, Lauren G. Zacharias, Feng Cai, Ralph J. DeBerardinis, Wenzhi Sun, Zeping Hu, Woo‐Ping Ge

This study maps the mouse brain metabolome using targeted metabolomics, creating detailed maps of 79 metabolites at high resolution.

bioRxiv · Dec 28, 2020 · PreprintNeuroscience

Reduction of neuronal activity mediated by blood-vessel regression in the brain

Xiaofei Gao, Jun-Liszt Li, Xingjun Chen, Bo Ci, Fei Chen, Nannan Lu, Bo Shen, Lijun Zheng, Jie‐Min Jia, Yating Yi, Shiwen Zhang, Ying-Chao Shi, Kaibin Shi, Nicholas E. Propson, Yubin Huang, , Woo‐Ping Ge

This study shows that blood vessel regression in the brain reduces neuronal activity by impairing mitochondrial metabolism and glutamate production.

bioRxiv · Sep 15, 2020 · PreprintNeuroscience