A phage parasite deploys a nicking nuclease effector to inhibit replication of its viral host
K. LeGault, Z. Barth, P. DePaola, K. Seed
This study identifies a phage-encoded nuclease, NixI, that inhibits replication of its viral host ICP1 by nicking its genome, preventing efficient packaging.
bioRxiv · Jul 12, 2021Microbiology