Cancer BiologybioRxiv
Mechanical-control of cell proliferation increases resistance to chemotherapeutic agents
I. Rizzuti, P. Mascheroni, S. Arcucci…·M. Delarue
The paper shows that compressive stress in pancreatic cancer spheroids reduces chemotherapeutic efficacy by decreasing cell proliferation.
DOI 10.1103/physrevlett.125.128103