Label-free Cell Tracking Enables Collective Motion Phenotyping in Epithelial Monolayers
S. Gu, R. M. Lee, Z. Benson, C. Ling, M. I. Vitolo, S. S. Martin, J. Chalfoun, W. Losert
The paper introduces an AI-based pipeline to track cell nuclei in phase contrast images and uses it to analyze collective motion in epithelial monolayers, finding that D2min correlates with metastatic potential.
bioRxiv · Dec 14, 2021Biophysics