The heterogeneity of the DNA damage response landscape determines patient outcomes in ovarian cancer
T. Walker, Z. Faraahi, m. price, A. Hawarden, C. Waddell, B. Russell, D. Jones, A. McCormick, N. Gavrielides, S. Tyagi, L. Woodhouse, B. Whalley, C. Roberts, E. Crosbie, R. Edmondson
The paper shows that DDR heterogeneity in ovarian cancer predicts patient outcomes and chemotherapy response by analyzing DDR pathway interactions and constructing predictive DDR signatures.
bioRxiv · Aug 3, 2021 · PreprintCell Biology