Resolvin D2/GPR18 signaling enhances monocytic myeloid-derived suppressor cell function to mitigate abdominal aortic aneurysm formation
P. Bellotti, Z. Ladd, V. Leroy, G. Su, S. Sharma, J. Hartman, J. Krebs, C. Viscardi, R. Maile, L. Moldawer, P. A. Efron, A. K. Sharma, G. R. Upchurch
This study shows RvD2/GPR18 signaling enhances M-MDSC function to reduce AAA formation by suppressing inflammation and vascular remodeling.
bioRxiv · Feb 23, 2024Immunology