A. K. Sharma

This study shows that MerTK-dependent efferocytosis by monocytic-MDSCs reduces post-lung transplant ischemia-reperfusion injury.

The paper introduces a computational framework linking chromatin structure to gene regulation using polymer models and Hi-C data, showing how CTCF deletion affects gene expression in limb development.

This study shows that common TMEM173 alleles HAQ and AQ reduce inflammation in SAVI mice by preventing CD4 T cell depletion and restoring T-regs.

This paper develops a gallium-68-labeled peptide radiotracer, [68Ga]Ga-AJ206, for non-invasive CD38 imaging in multiple myeloma using PET, showing high specificity and utility in monitoring therapy response.

This study shows that methylglyoxal (MG) regulates tomato fruit ripening by controlling ethylene biosynthesis through the SlGLY14 gene.

This study identifies SlERF.D7 as a ripening regulator in tomatoes that activates SlARF2A/B to control ripening by integrating auxin and ethylene signaling.

This paper develops a cell-based assay to screen for FtsZ inhibitors and identifies a salt bridge-mediated resistance mechanism to PC190723 in Helicobacter pylori FtsZ.

This study identifies five metabolites associated with the onset of dental caries using an ex-vivo model and metabolomics, linking them to specific bacterial taxa.

The paper tests tolfenamic acid's toxicity to Gyps vultures and finds it safe at concentrations found in cattle carcasses, unlike other NSAIDs.

This study identifies NSC49L as a PP2A agonist that sensitizes FOLFOX-resistant colorectal cancer cells to TRAIL by downregulating the AKT1/mTOR/4EBP1-axis and p21 translation.

This study investigates the origin and adaptation of SARS-CoV-2 through recombination events and mutations in the spike protein, linking these factors to its emergence in humans.

The paper uses CT scans to analyze hip pathology in a Smilodon fossil, concluding it suffered from hip dysplasia, suggesting social behavior in the species.

The paper investigates charge-dependent phase separation in chromatin using electron spectroscopic imaging and shows that chromatin organization changes with histone modifications and environmental factors.

This study shows that administering SCGN improves insulin response and alleviates diabetic complications in high-fat diet-fed animals.