Conformationally responsive dyes enable protein-adaptive Differential Scanning Fluorometry
T. Wu, J. C. Yu, A. Suresh, Z. J. Gale-Day, M. G. Alteen, A. S. Woo, Z. Millbern, O. T. Johnson, E. C. Carroll, C. L. Partch, D. Fourches, N. R. Vinueza, D. J. Vocadlo, J. E. Gestwicki
This paper introduces paDSF, a protein-adaptive Differential Scanning Fluorometry method that improves compatibility with proteins and expands observable processes.
bioRxiv · Jan 23, 2023 · PreprintBiochemistry