BiochemistrybioRxivPreprint
Correcting mutant CFTR with a stabilizing nanobody reveals a novel active conformation of the channel
Marie Overtus, James N. Charlick, Tihomir Rubil…·Cédric Govaerts
This study uses a nanobody to stabilize mutant CFTR, revealing a novel active conformation and improving its function in cystic fibrosis.
DOI 10.1101/2025.10.08.681081