BiophysicsACS SensorsPeer-reviewed
Fluorogenic Aptamer Optimizations on a Massively Parallel Sequencing Platform
Yu-An Kuo, Y.-I. Chen, Naseem Siraj…·Hsin‐Chih Yeh
This paper optimizes a DNA-based fluorogenic aptamer (D-FAP) using a screening-and-simulation pipeline on a repurposed sequencing platform, achieving improved fluorescence properties.