Author

Zeyu Chen

Peking University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Genomics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

Allison R. GreenplateiD· 1 shared Amy E. BaxteriD· 1 shared Cuiting Zhong· 1 shared David B. WeineriD· 1 shared Divij MathewiD· 1 shared E. John WherryiD· 1 shared Hongyi XiniD· 1 shared Jennifer E. WuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Allison R. GreenplateORCID

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2 papers

Recent·Most cited

RegDesign-Bench: Benchmarking computational methods for cell-type-specific regulatory DNA design

Jiaying Xu, Zekun Guo, Cuiting Zhong, Qijin Yin, Yuan He, Zeyu Chen, Hongyi Xin, Peiran Jin, Pan Deng

RegDesign-Bench evaluates computational methods for designing cell-type-specific regulatory DNA, showing that performance on individual metrics does not guarantee overall effectiveness.

bioRxiv · Oct 19, 2026 · PreprintGenomics

PD-1 blockade drug holiday improves exhausted progenitor CD8 T cell (Tpex) reinvigoration by avoiding Tpex adaptive resistance

Shin Foong Ngiow, Ryan P. O’Connell, Sasikanth Manne, Yinghui Jane Huang, Josephine Ruth Giles, Víctor Alcalde, Divij Mathew, Max Klapholz, Kito Nzingha, Zeyu Chen, Amy E. Baxter, Kunal P. Patel, Jennifer E. Wu, Ryan P. Staupe, Mohammed-Alkhatim A. Ali, , E. John Wherry

The paper shows that a drug holiday during PD-1 blockade improves reinvigoration of exhausted T cells by restoring progenitor cell function and reducing adaptive resistance.

bioRxiv · May 18, 2026 · PreprintImmunology