Zeyu Wang

SpatioCell: Deep Integration of Histology and Spatial Transcriptomics for Profiling the Cellular Microenvironment at Single-Cell Level

SpatioCell integrates histology and spatial transcriptomics to extract single-cell resolution cell type and expression information from ST data, revealing microenvironment features in triple negative breast cancer.

The amplitude and latency of the earliest signal in V1 encode bottom-up saliency by feature conjunction

The paper shows that early V1 neural signals encode bottom-up saliency based on feature conjunction, with latency and amplitude predicting behavioral performance.

Non-invasive and painless mid-infrared modulation increases collagen in human and mouse skin

Mid-infrared modulation promotes collagen production in human and mouse skin without pain or trauma.

Hidden stop codons orchestrate mRNA fate by ambushing ribosomal frameshifting associated with codon usage

The paper shows hidden stop codons promote mRNA decay by causing ribosomal frameshifting in fungi and human cells, disrupting circadian rhythms and stabilizing mRNAs with nonoptimal codons.