Hierarchical latent representations reveal protein organization for functional discovery and design
Zhengyang Guo, Zi Wang, Shimin Wang, Yongping Chai, Kaiming Xu, Ming Li, Wei Li, Guangshuo Ou
This paper develops a hierarchical sequence-based framework to infer distributed protein organization, identifies novel ciliary proteins, and enables synthetic protein design.
bioRxiv · Jun 1, 2026 · PreprintBioinformatics