Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewed
Structural basis of peptidomimetic agonism revealed by small molecule GLP-1R agonists Boc5 and WB4-24
Zhaotong Cong, Qingtong Zhou, Yang Li…·Ming‐Wei Wang
This paper reports cryo-EM structures of small molecule GLP-1R agonists Boc5 and WB4-24, revealing a novel binding pocket and mechanism for peptidomimetic agonism.
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