Developmental BiologyCell ReportsPeer-reviewed
Translational regulation of non-autonomous mitochondrial stress response promotes longevity
Jianfeng Lan, Jarod A. Rollins, Xiao Zang…·Di Chen
The paper identifies translational repression of CYC-2.1 in the germline as a mechanism that extends lifespan through non-autonomous activation of UPRmt and AMPK in C. elegans.
73 citations