Cancer BiologyFrontiers in OncologyPeer-reviewed
Saracatinib synergizes with enzalutamide to downregulate androgen receptor activity in castration resistant prostate cancer
Ralph E. White, Maxwell Henry Bannister, Abderrahman Day…·Justin M. Drake
This study shows that combining saracatinib with enzalutamide reduces androgen receptor activity and DNA replication in CRPC cell lines, leading to increased apoptosis.
7 citations