Liwei Jiang

The paper identifies four broadly neutralizing antibodies from a breakthrough infection donor that target conserved epitopes on SARS-CoV-2's RBD and NTD, showing synergistic neutralization when combined.

The paper examines how sequential Omicron infections affect ancestral SARS-CoV-2 immune imprinting, finding that it persists on the RBD but not the NTD.

The paper shows that B cells from ancestral SARS-CoV-2 infections can develop broad neutralization against multiple sarbecoviruses after repeated immune challenges.

This study identifies hypermutated IGHV3-53/3-66 antibodies from breakthrough infections that broadly neutralize SARS-CoV-2 variants including BQ and XBB.