Cancer BiologyThe Journal of Experimental MedicinePeer-reviewed
Unleashing the Power of NR4A1 Degradation as a Novel Strategy for Cancer Immunotherapy
Lei Wang, Yufeng Xiao, Yuewan Luo…·Weizhou Zhang
This paper develops a PROTAC molecule (NR-V04) that degrades NR4A1, leading to tumor inhibition and immune modulation in melanoma.
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