Author

Marcel P. Trefny

University of BaselORCID 0000-0001-6755-7899Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Approach:deep learning· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Alfred ZippeliusiD· 2 shared Kirsten D. MertziD· 2 shared Adrian GottschlichiD· 1 shared Adrien DaigeleriD· 1 shared Aljaž HojskiiD· 1 shared Anand S. BhagwatiD· 1 shared Andrea Romagnani· 1 shared Andreas ZinggiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersImmunology

Alfred ZippeliusORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 21, 2026

A CAR T cell-amplified suppressive B cell circuit in AML

Adrian Gottschlich, Vladyslav Kavaka, Thomas Alexander Janert…·Sebastian Kobold

The paper identifies suppressive atypical memory B cells in AML that are amplified by CAR T cell interactions and shows that targeting both B cells and AML blasts can overcome this suppression.

DOI 10.64898/2026.10.12.758644

humanbulk RNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintAug 26, 2025

CD39 defines a cytotoxic tumor-associated NK cell state responsive to NKG2A blockade in lung cancer

Clara Serger, Lucas Rebuffet, Michael T. Sandholzer…·Alfred Zippelius

The paper identifies CD39+ tumor-associated NK cells as a cytotoxic effector state in NSCLC responsive to NKG2A blockade through multiomic analysis.

DOI 10.1101/2025.08.26.672316

humanscRNA-seq

𝕏 PostBluesky

ImmunologybioRxivPreprintOct 4, 2023

Multimodal single-cell profiling of T cell specificity and reactivity in lung cancer

Florian Bieberich, Rodrigo Vazquez-Lombardi, Huixin Jin…·Sai T. Reddy

This study uses multimodal single-cell profiling to analyze T cell specificity and reactivity in lung cancer patients, identifying tumor- and virus-reactive T cells and their functional states.

DOI 10.1101/2023.10.04.560863

humanscRNA-seq

𝕏 PostBluesky