Author

John Frater

University of OxfordORCID 0000-0001-7163-7277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1 Genetics· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 3 Approach:Bayesian inference· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Philip GoulderiD· 2 shared Aime Bienfait IgiranezaiD· 1 shared Andreas GrolliD· 1 shared ANGELA E. R. TAYLORiD· 1 shared Angela Ruth McLeaniD· 1 shared Anna Csala· 1 shared Annette OxeniusiD· 1 shared Cecilia JayiD· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Philip GoulderORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BioinformaticsPLoS Computational BiologyPeer-reviewedNov 20, 2024

Learning patterns of HIV-1 co-resistance to broadly neutralizing antibodies with reduced subtype bias using multi-task learning

Aime Bienfait Igiraneza, Panagiota Zacharopoulou, Robert Hinch…·Christophe Fraser

This paper develops a multi-task learning model to predict HIV-1 resistance to multiple broadly neutralizing antibodies, showing it reduces subtype bias and identifies co-resistance patterns.

10 citations

humanmachine learning (classical)

𝕏 PostBluesky

ImmunologyFrontiers in ImmunologyPeer-reviewedFeb 28, 2024

Gonadal androgens are associated with decreased type I interferon production by pDCs and increased IgG titres to BNT162b2 following co-vaccination with live attenuated influenza vaccine in adolescents

Oliver L. Sampson, Cecilia Jay, Emily Adland…·Philip Goulder

The paper investigates how gonadal androgens affect type I interferon production by pDCs and IgG titres to BNT162b2 in adolescents co-vaccinated with LAIV.

7 citations

humanbulk RNA-seq

𝕏 PostBluesky

GeneticsNature CommunicationsPeer-reviewedJul 9, 2019

Mapping the drivers of within-host pathogen evolution using massive data sets

Duncan S. Palmer, Isaac Turner, Sarah J. Fidler…·Gil McVean

The paper develops a Bayesian method to detect host influences on pathogen evolution using large datasets, demonstrating improved precision in identifying HLA-induced selection in HIV-1.

11 citations

humanwhole-genome sequencing

𝕏 PostBluesky